Sarett Patent No. 2,462,133 Process of Treating Pregnene Compounds
Lewis Sarett, a native of Champaign, Illinois, was born in 1917 and later attended Northwestern University, where he graduated in 1939. He also received a Ph.D. from Princeton University shortly before joining the Merck Research Laboratories in Rahway, N.J. as a research chemist.
In 1944, Sarett created the first synthetic cortisone for Merck, as part of a U.S. government effort to improve military medicine. It's true value was unearthed four years later at the Mayo Clinic when the hormone was proven to be effective in the treatment of rheumatoid arthritis.
Sarett and his colleagues later initiated an alternative synthesis using raw materials derived from coal, air, lime and water, which later led to other alternative processes which were independent of naturally-occuring starting materials. That work was Sarett's greatest achievement and he received the American Chemical Society Award for Creative Chemistry in 1964, one of several honors and awards he collected during his lifetime. In addition to his patents, Sarett also collaborated on more than 100 technical papers and patent abstracts.
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