INVENTORS HALL OF FAME
Collip
Patent No. 1,469,994 Extract Obtainable from the Mammalian Pancreas Isolated, Purified Insulin
Born in Belleville, Ontario, biochemist James B. Collip earned his B.A. from Trinity College in 1912 and his M.A. in 1913. At the University of Toronto, he earned a Ph.D. in biochemistry in 1916. He later conducted research at the University of Alberta, McGill University in Montreal, and the University of Western Ontario.
Collip developed the process for producing enough pure insulin for clinical trials, a key contribution to the treatment of diabetes.
After Charles Best and Frederick Banting discovered insulin and proved that it could save the lives of diabetics, they encountered trouble finding ways to purify and extract the natural hormone. Collip solved the problem by devising the first successful process that could remove harmful impurities from insulin while retaining its lifesaving qualities.
Days after he produced a batch of his extract, it was used to save a 14-year-old boy who was near death from the ravages of diabetes.
Collip went on to become a leading endocrinologist and a worldwide authority on the properties of insulin. He received numerous professional awards and honorary degrees.
James Collip died on June 19, 1965.
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